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Metabolism (breakdown) of sildenafil is slowed by aging, liver and kidney dysfunction, and concurrent use of certain medications (such as erythromycin -- an antibiotic, and protease inhibitors, for HIV). Slowed breakdown allows sildenafil to accumulate in the body and potentially may increase the risk of side effects. Therefore in men over 65, in men with substantial kidney and liver disease, and in men who also are taking protease inhibitors, the doctor will initiate sildenafil at a lower dose (25 mg) to avoid accumulation of sildenafil in the body. A protease inhibitor ritonavir (Norvir) is especially potent in increasing the accumulation of sildenafil, thus men who are taking Norvir should not take sildenafil doses higher than 25 mg and at a frequency of no greater than once in 48 hours. What are vacuum devices? Mechanical vacuum devices cause an erection by creating a vacuum around the penis that draws blood into the penis, engorging it, and expanding it. One variation of the vacuum device involves a semi-rigid rubber sheath that is placed on the penis and remains there after attaining erection and during intercourse. Brand cialis for sale What Causes Male Sexual Problems? Physical causes: Many physical and/or medical conditions can cause problems with sexual function. These conditions include diabetes, heart and vascular (blood vessel) disease, neurological disorders, hormonal imbalances, chronic diseases such as kidney or liver failure, and alcoholism and drug abuse. In addition, the side effects of certain medications, including some antidepressant drugs, can affect sexual desire and function. Therefore, the dose and frequency of tadalafil has to be lowered in the following examples:Men with severe liver disease should not take tadalafil. Men with mild to moderate liver disease should not exceed tadalafil dose of 10 mg once daily. How effective is vardenafil (Levitra)? Vardenafil was evaluated in four multicenter, randomized, placebo-controlled trials involving more than 2,400 men (78% white, 7% black, 2% Asian, 3% Hispanic) with erectile dysfunction. Two of these trials were conducted in special erectile dysfunction populations; one in men with diabetes mellitus, another in men who developed erectile dysfunction after prostate surgery. The doses of vardenafil in the four studies were 5 mg, 10 mg, and 20 mg. viagra online express shipping buy viagra online
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There are no formal tests to diagnose erectile dysfunction. Some blood tests are generally done to exclude underlying disease, such as hypogonadism and prolactinoma. Diabetes is considered a disorder, but is also a risk. Impotence is also related to generally poor physical health, poor dietary habits, obesity, and most specifically cardiovascular disease such as coronary artery disease and peripheral vascular disease. Erectile Dysfunction (Impotence) - Erectile dysfunction (ED) means that you cannot get a proper erection. There are various causes. However, most cases are due to narrowing of the arteries that take blood to the penis. This is due to a build up of atheroma in these arteries. This is similar to the way the heart arteries are affected in people with heart disease. As with heart disease, smoking and heavy alcohol drinking are important risk factors. There are various other causes of ED listed below. Most cases of ED can be treated. The common treatment is to take a tablet before you plan to have sex. There are also various other treatment options. If you have ED, you may also be advised on lifestyle factors and treatments to minimise your risk of developing heart disease.